Effect of rearing condition on anxiety-like behavior assessed in the elevated plus-maze. Bar graph illustrating the effect of adolescent rearing condition on mean (± SEM) open arm time , % open arm entries and the number of closed arm entries in the plus-maze for group housed (GH), socially isolated (SI) and age-matched standard housed (STD) rats. The test was conducted on PD 72 for all groups. (N==16 GH, 17 SI, 17 STD; *, significant difference between GH and SI rats; Ψ, significant difference between GH and STD rats (P < 0.05); NS, no significant difference).