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. 2012 Jul 19;6(1):125–134. doi: 10.1242/dmm.009167

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© 2012. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms.

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Fig. 1. — Challenge with oxazolone results in epithelial hyperplasia and influx of inflammatory cells into the epidermis and dermis and keratosis as observed in immunocompetent mice. (A–C) HE-stained photomicrographs of skin sections from BALB/C mice: (A) no treatment, (B) challenged with ethanol and (C) challenged with oxazolone. (D–F) HE-stained skin sections from NOD-scid IL2Rγ^null mice: (D) non-engrafted no treatment, (E) non-engrafted challenged with oxazolone and (F) engrafted challenged with oxazolone. Arrows indicate epithelial hyperplasia. Scale bars: 50 μm.