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. 2012 Jul 19;6(1):125–134. doi: 10.1242/dmm.009167

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© 2012. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms.

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Fig. 3. — Challenge with oxazolone results in histological changes in NOD-scid IL2Rγ^null mice engrafted with PMBCs derived from patients with AD. Histological changes were classified according to a histological score and depicted in a boxplot diagram. Sample sizes: non-engrafted n=4, non-AD n=9 and AD n=12. P<0.01 for AD vs non-AD treated with oxazolone. P=0.22 for AD versus non-AD treated with ethanol (Kruskal-Wallis test followed by multiple comparisons).