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. 2012 Aug 23;6(1):146–159. doi: 10.1242/dmm.009852

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© 2012. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms.

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Fig. 2. — Progressive glafenine-induced injury over 0–12 hours is centered on the intestine. (A) AO-positive tube formation, n=13. (B) Segment 2 histological score, n≥9. The 0 and 12-hour time points are recapitulated from Fig. 1. (C) Histology at 3 hours. (D) H&E sections of livers of zebrafish exposed to 0, 3, 6 and 12 hours of glafenine. Mild hydropic changes are seen at 6 hours. Scale bars: 50 μm. *P<0.05, ***P<0.001.