Skip to main content
. 2012 Nov 16;154(1):36–44. doi: 10.1210/en.2012-1725

Fig. 3.

Fig. 3.

ChREBP ASO modestly improves peripheral insulin sensitivity. Glucose metabolism was assessed using the hyperinsulinemic-euglycemic clamp. A, Basal endogenous glucose production was unchanged between control ASO and ChREBP ASO for each group; B, ChREBP ASO increased the glucose infusion rate in the fructose-fed rats but not the safflower-oil-treated rats; C and D, insulin-stimulated endogenous glucose production (C) and whole-body glucose disposal (D) during the hyperinsulinemic-euglycemic clamps; E, the increases in glucose disposal in the fructose-fed ChREBP ASO-treated rats can be attributed to increases in glucose disposal in the muscle. #, P = 0.053; *, P < 0.05.