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Mitochondria O2 ∙− production in Leishmania amazonensis promastigotes treated with geranylgeraniol for 2 h. Mitochondria O2 ∙− production was evaluated using the fluorescent probe MitoSOX. Asterisks indicate significant difference relative to the control group (untreated parasites) as identified by variance analysis (one-way) with post hoc Tukey testing (*P ≤ 0.05). Results are expressed as mean fluorescence (in arbitrary units) ± SD of at least three independent experiments.
