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. 2012 Dec 24;199(7):1047–1055. doi: 10.1083/jcb.201209050

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© 2012 Chai et al.

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Figure 4. — Midbody degradation in other cell lineages. (A, left) Midbodies from C. elegans embryonic lineages normally degrade when L1 larvae hatch. Persistent midbodies remain in ced-1 (middle) but not in ced-3 mutants (right). Midbodies were visualized by P_zen-4::zen-4::gfp. Dotted lines show the C. elegans periphery. (B) Midbody degradation in the pharynx terminal bulb (top) and tail (bottom) of the late L4 animals in WT (left), ced-1 (middle), and ced-3 (right) mutant. Arrows show the persistent midbodies in ced-1 mutants. (C) Quantifications of midbody degradation in embryonic (left) and postembryonic (pharynx terminal bulb [middle] or tail [right]) lineages. *, P < 0.01, the Student’s t test. Error bars represent SDs. Bars, 5 µm.