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. Author manuscript; available in PMC: 2012 Dec 24.
Published in final edited form as: Electrophoresis. 2008 Apr;29(7):1415–1422. doi: 10.1002/elps.200700777

Table 1.

Results of thrombin-aptamer dissociation constant and kinetic rate constants.

T0 (nM) 150 250 300 350 600
Kd (nM) 37 ± 4 38 ± 8 46 ± 7 50 ± 8 198 ± 36
k− (s−1) 0.15±0.01 0.09±0.00 0.12±0.02 0.08±0.01 0.08±0.01
k+ (pM−1s−1) 4.1 ± 0.7 2.4 ± 0.6 2.7 ± 0.3 1.7 ± 0.1 0.4 ± 0.1

Note: The aptamer concentration was fixed at 500 nM.