Table 2.
Health-related quality-of-life questionnaire submission rates: Physical Function, Mental Health, and Vitality Scales by treatment group and assessment time
| Assessment time | Questionnaire submitted* | Physical Function Score usable† | Mental Health Score usable‡ | Vitality Score usable§ | ||||
|---|---|---|---|---|---|---|---|---|
| Finasteride No. (%) | Placebo No. (%) | Finasteride No. (%) | Placebo No. (%) | Finasteride No. (%) | Placebo No. (%) | Finasteride No. (%) | Placebo No. (%) | |
| Enrollment | 9422 (100) | 9454 (100) | 9420 (100) | 9449 (99.9) | 9399 (99.7) | 9423 (99.6) | 9406 (99.8) | 9435 (99.8) |
| Time after randomization | ||||||||
| 6 mo | 8529 (94.5) | 8711 (94.7) | 8484 (94.0) | 8669 (94.3) | 8476 (93.9) | 8661 (94.2) | 8476 (93.9) | 8665 (94.2) |
| 1 y | 8193 (97.1) | 8591 (97.7) | 8185 (97.0) | 8578 (97.6) | 8174 (96.8) | 8564 (97.4) | 8175 (96.8) | 8565 (97.4) |
| 2 y | 7289 (96.9) | 7902 (96.9) | 7273 (96.7) | 7885 (96.7) | 7256 (96.5) | 7870 (96.5) | 7259 (96.5) | 7868 (96.5) |
| 3 y | 6720 (97.0) | 7330 (96.6) | 6695 (96.6) | 7310 (96.4) | 6679 (96.4) | 7298 (96.2) | 6686 (96.5) | 7297 (96.2) |
| 4 y | 6272 (97.1) | 6917 (97.1) | 6236 (96.5) | 6883 (96.6) | 6220 (96.3) | 6855 (96.2) | 6223 (96.3) | 6854 (96.2) |
| 5 y | 5948 (97.1) | 6515 (96.6) | 5917 (96.6) | 6472 (96.0) | 5884 (96.1) | 6440 (95.5) | 5886 (96.1) | 6442 (95.5) |
| 6 y | 5605 (96.4) | 6176 (96.3) | 5557 (95.6) | 6119 (95.4) | 5532 (95.2) | 6106 (95.2) | 5532 (95.2) | 6107 (95.2) |
| 7 y‖ | 5034 (96.9) | 5462 (96.7) | 4961 (95.5) | 5393 (95.5) | 4941 (95.1) | 5374 (95.1) | 4939 (95.1) | 5374 (95.1) |
* The primary reason for missing forms was a participant going off the assigned prevention agent, including men who were diagnosed with prostate cancer during the trial and men who died. Questionnaire submission rates were calculated for each treatment arm as the number of questionnaires submitted divided by the number of participants expected to complete the questionnaire (ie, the number on study long enough to reach specific assessment point).
† If more than 2 items omitted, the Physical Functioning score is not usable.
‡ If more than 1 item omitted, the Mental Health score is not usable.
§ If more than 1 item omitted, the Vitality score is not usable.
‖ Due to early trial closure, approximately 300 participants completed a final questionnaire at 6 y 6 mo or at 6 y 9 mo instead of at 7 y.