Relative contributions of SapA and the SapBC permeases to LL-37 resistance. A, Survival of 35000HP(pLSSK), 35000HPsapBC (pLSSK), and 35000HPsapBC (psapBC) exposed to the indicated concentrations of LL-37. The data represent the mean and standard error of 5 independent assays. Asterisks indicate statistical significance from the parent strain (P < .05). B, Survival of 35000HP (pLSSK), 35000HPsapA (pLSSK), and 35000HPsapBC (pLSSK) exposed to the indicated concentrations of LL-37. The data represent the mean and standard error of 8 independent assays. Asterisks indicate statistical significance from the sapBC mutant (P < .05).