Table S2.
List of the 283 single genes.
| Gene symbol | Description |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ABTB2 | Ankyrin repeat and BTB (POZ) domain containing 2 |
| ACD | Adrenocortical dysplasia homolog (mouse) |
| ADFP | Adipose differentiation-related protein |
| ADH1B | Alcohol dehydrogenase IB (class I), beta polypeptide |
| ADRA2A | Adrenergic, alpha-2A-, receptor |
| ADRM1 | Adhesion regulating molecule 1 |
| ALDH1A1 | Aldehyde dehydrogenase 1 family, member A1 |
| ALDH2 | Aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDH6A1 | Aldehyde dehydrogenase 6 family, member A1 |
| APOD | Apolipoprotein D |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| ATP9A | ATPase, Class II, type 9A |
| AURKB | Aurora kinase B |
| BARD1 | BRCA1 associated RING domain 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BCL2L1 | BCL2-like 1 |
| BRCA1 | Breast cancer 1, early onset |
| BUB1 | BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) |
| BUB1B | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) |
| C6 | Complement component 6 |
| C7ORF24 | Chromosome 7 open reading frame 24 |
| CACNA1D | Calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CARS | Cysteinyl-tRNA synthetase |
| CAT | Catalase |
| CCNA2 | Cyclin A2 |
| CCNB1 | Cyclin B1 |
| CCNB2 | Cyclin B2 |
| CCNE2 | Cyclin E2 |
| CCNF | Cyclin F |
| CCT5 | Chaperonin containing TCP1, subunit 5 (epsilon) |
| CCT6A | Chaperonin containing TCP1, subunit 6A (zeta 1) |
| CD44 | CD44 molecule (Indian blood group) |
| CDC2 | Cell division cycle 2, G1 to S and G2 to M |
| CDC20 | CDC20 cell division cycle 20 homolog (S. cerevisiae) |
| CDC25B | Cell division cycle 25B |
| CDC25C | Cell division cycle 25C |
| CDC34 | Cell division cycle 34 |
| CDC45L | CDC45 cell division cycle 45-like (S. cerevisiae) |
| CDK8 | Cyclin-dependent kinase 8 |
| CDKN3 | Cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) |
| CDO1 | Cysteine dioxygenase, type I |
| CENPE | Centromere protein E, 312 kDa |
| CENPF | Centromere protein F, 350/400 ka (mitosin) |
| CH25H | Cholesterol 25-hydroxylase |
| CHAF1B | Chromatin assembly factor 1, subunit B (p60) |
| CIRBP | Cold inducible RNA binding protein |
| CKAP5 | Cytoskeleton associated protein 5 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CNN3 | Calponin 3, acidic |
| CNTN1 | Contactin 1 |
| CP | Ceruloplasmin (ferroxidase) |
| CREBL2 | CAMP responsive element binding protein-like 2 |
| CRIM1 | Cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CSTF1 | Cleavage stimulation factor, 3′ pre-RNA, subunit 1, 50 kDa |
| CTPS | CTP synthase |
| CTSD | Cathepsin D (lysosomal aspartyl peptidase) |
| CTSL | Cathepsin L |
| CX3CR1 | Chemokine (C-X3-C motif) receptor 1 |
| CYP4B1 | Cytochrome P450, family 4, subfamily B, polypeptide 1 |
| CYP4F12 | Cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX39 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 |
| DLG7 | Discs, large homolog 7 (Drosophila) |
| DLX2 | Distal-less homeobox 2 |
| DOCK1 | Dedicator of cytokinesis 1 |
| DPT | Dermatopontin |
| DUSP1 | Dual specificity phosphatase 1 |
| DUSP4 | Dual specificity phosphatase 4 |
| DYRK2 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| EBP | Emopamil binding protein (sterol isomerase) |
| EDG1 | Endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 |
| EGR2 | Early growth response 2 (Krox-20 homolog, Drosophila) |
| ELOVL5 | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3- like, yeast) |
| ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) |
| EPHX2 | Epoxide hydrolase 2, cytoplasmic |
| ESPL1 | Extra spindle poles like 1 (S. cerevisiae) |
| EVPL | Envoplakin |
| EXO1 | Exonuclease 1 |
| EZH2 | Enhancer of zeste homolog 2 (Drosophila) |
| F3 | Coagulation factor III (thromboplastin, tissue factor) |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FANCG | Fanconi anemia, complementation group G |
| FAS | Fas (TNF receptor superfamily, member 6) |
| FBLN1 | Fibulin 1 |
| FBLN5 | Fibulin 5 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FEN1 | Flap structure-specific endonuclease 1 |
| FGL2 | Fibrinogen-like 2 |
| FLJ22531 | – |
| FMO2 | Flavin containing monooxygenase 2 (non-functional) |
| FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog |
| FOXM1 | Forkhead box M1 |
| FRZB | Frizzled-related protein |
| FUCA1 | Fucosidase, alpha-L-1, tissue |
| GABARAP | GABA(A) receptor-associated protein |
| GAD1 | Glutamate decarboxylase 1 (brain, 67 kDa) |
| GALK1 | Galactokinase 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GGCX | Gamma-glutamyl carboxylase |
| GLA | Galactosidase, alpha |
| GLI1 | Glioma-associated oncogene homolog 1 (zinc finger protein) |
| GMPS | Guanine monphosphate synthetase |
| GNG11 | Guanine nucleotide binding protein (G protein), gamma 11 |
| GNG12 | Guanine nucleotide binding protein (G protein), gamma 12 |
| GPSM2 | G-protein signalling modulator 2 (AGS3-like, C. elegans) |
| GRIK1 | Glutamate receptor, ionotropic, kainate 1 |
| GSTM3 | Glutathione S-transferase M3 (brain) |
| GUK1 | Guanylate kinase 1 |
| GYS2 | Glycogen synthase 2 (liver) |
| H2AFZ | H2A histone family, member Z |
| HIST1H3D | Histone cluster 1, H3d |
| HMGB2 | High-mobility group box 2 |
| HMMR | Hyaluronan-mediated motility receptor (RHAMM) |
| HNMT | Histamine N-methyltransferase |
| HNRPAB | Heterogeneous nuclear ribonucleoprotein A/B |
| HNRPH2 | Heterogeneous nuclear ribonucleoprotein H2 (H′) |
| HPN | Hepsin (transmembrane protease, serine 1) |
| HPRT1 | Hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) |
| IFNGR2 | Interferon gamma receptor 2 (interferon gamma transducer 1) |
| IGFBP4 | Insulin-like growth factor binding protein 4 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 |
| ITM2A | Integral membrane protein 2A |
| ITPR1 | Inositol 1,4,5-triphosphate receptor, type 1 |
| JAK2 | Janus kinase 2 (a protein tyrosine kinase) |
| KCTD12 | Potassium channel tetramerisation domain containing 12 |
| KIF11 | Kinesin family member 11 |
| KIF13B | Kinesin family member 13B |
| KIF14 | Kinesin family member 14 |
| KIF2C | Kinesin family member 2C |
| KIFC1 | Kinesin family member C1 |
| KIAA0101 | KIAA0101 |
| KIAA0247 | KIAA0247 |
| KIAA0286 | – |
| KIAA0319 | KIAA0319 |
| LAMA2 | Laminin, alpha 2 (merosin, congenital muscular dystrophy) |
| LARP1 | La ribonucleoprotein domain family, member 1 |
| LEP | Leptin (obesity homolog, mouse) |
| LIG1 | Ligase I, DNA, ATP-dependent |
| LMNB1 | Lamin B1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LPHN2 | Latrophilin 2 |
| LPL | Lipoprotein lipase |
| LRIG1 | Leucine-rich repeats and immunoglobulin-like domains 1 |
| LRP2 | Low density lipoprotein-related protein 2 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAPRE1 | Microtubule-associated protein, RP/EB family, member 1 |
| MARS | Methionine-tRNA synthetase |
| MCM3 | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) |
| MCM6 | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) |
| MCM7 | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) |
| MEIS1 | Meis1, myeloid ecotropic viral integration site 1 homolog (mouse) |
| MELK | Maternal embryonic leucine zipper kinase |
| MGP | Matrix Gla protein |
| MKI67 | Antigen identified by monoclonal antibody Ki-67 |
| MN1 | Meningioma (disrupted in balanced translocation) 1 |
| MRPL12 | Mitochondrial ribosomal protein L12 |
| MT2A | Metallothionein 2A |
| MTHFD2 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| MVD | Mevalonate (diphospho) decarboxylase |
| MYBL2 | v-myb myeloblastosis viral oncogene homolog (avian)-like 2 |
| NCOA1 | Nuclear receptor coactivator 1 |
| NDUFA9 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39 kDa |
| NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9 |
| NEK2 | NIMA (never in mitosis gene a)-related kinase 2 |
| NME5 | Non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase) |
| NNAT | Neuronatin |
| NP | Nucleoside phosphorylase |
| NR3C2 | Nuclear receptor subfamily 3, group C, member 2 |
| NTRK2 | Neurotrophic tyrosine kinase, receptor, type 2 |
| NUDT1 | Nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| NUP155 | Nucleoporin 155 kDa |
| NUP62 | Nucleoporin 62 kDa |
| NVL | Nuclear VCP-like |
| OMD | Osteomodulin |
| P4HA2 | Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II |
| PDCD4 | Programmed cell death 4 (neoplastic transformation inhibitor) |
| PDE4A | Phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) |
| PDZRN3 | PDZ domain containing RING finger 3 |
| PFKP | Phosphofructokinase, platelet |
| PHLDA2 | Pleckstrin homology-like domain, family A, member 2 |
| PIN1 | Protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1 |
| PIP | Prolactin-induced protein |
| PIR | Pirin (iron-binding nuclear protein) |
| PKMYT1 | Protein kinase, membrane associated tyrosine/threonine 1 |
| PLK4 | Polo-like kinase 4 (Drosophila) |
| PLP2 | Proteolipid protein 2 (colonic epithelium-enriched) |
| PNMA2 | Paraneoplastic antigen MA2 |
| PNRC1 | Proline-rich nuclear receptor coactivator 1 |
| POLD1 | Polymerase (DNA directed), delta 1, catalytic subunit 125 kDa |
| POLR2H | Polymerase (RNA) II (DNA directed) polypeptide H |
| POLS | Polymerase (DNA directed) sigma |
| PRAME | Preferentially expressed antigen in melanoma |
| PSD3 | Pleckstrin and Sec7 domain containing 3 |
| PSMB3 | Proteasome (prosome, macropain) subunit, beta type, 3 |
| PSMB7 | Proteasome (prosome, macropain) subunit, beta type, 7 |
| PSMD1 | Proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 |
| PSMD11 | Proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PTDSR | Phosphatidylserine receptor |
| PTGER3 | Prostaglandin E receptor 3 (subtype EP3) |
| PTGER4 | Prostaglandin E receptor 4 (subtype EP4) |
| PTPRT | Protein tyrosine phosphatase, receptor type, T |
| PTTG1 | Pituitary tumor-transforming 1 |
| QDPR | Quinoid dihydropteridine reductase |
| RABGGTA | Rab geranylgeranyltransferase, alpha subunit |
| RABIF | RAB interacting factor |
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) |
| RAD51AP1 | RAD51 associated protein 1 |
| RAE1 | RAE1 RNA export 1 homolog (S. pombe) |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RBMS3 | RNA binding motif, single stranded interacting protein |
| RDBP | RD RNA binding protein |
| RECQL4 | RecQ protein-like 4 |
| RFC3 | Replication factor C (activator 1) 3, 38 kDa |
| RFC4 | Replication factor C (activator 1) 4, 37 kDa |
| RGS5 | Regulator of G-protein signalling 5 |
| RICS | – |
| RNASEH2A | Ribonuclease H2, subunit A |
| RRM1 | Ribonucleotide reductase M1 polypeptide |
| RRM2 | Ribonucleotide reductase M2 polypeptide |
| RTN1 | Reticulon 1 |
| SAC3D1 | SAC3 domain containing 1 |
| SC5DL | Sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like |
| SDS | Serine dehydratase |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SEC61G | Sec61 gamma subunit |
| SELE | Selectin E (endothelial adhesion molecule 1) |
| SEMA3E | Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
| SERPINA1 | Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SF3B4 | Splicing factor 3b, subunit 4, 49 kDa |
| SFRP4 | Secreted frizzled-related protein 4 |
| SFRS5 | Splicing factor, arginine/serine-rich 5 |
| SH3BGRL | SH3 domain binding glutamic acid-rich protein like |
| SIAHBP1 | – |
| SIX1 | Sine oculis homeobox homolog 1 (Drosophila) |
| SLBP | Stem-loop (histone) binding protein |
| SLC14A1 | Solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC16A3 | Solute carrier family 16, member 3 (monocarboxylic acid transporter 4) |
| SLC25A1 | Solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 |
| SLC4A7 | Solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLIT2 | Slit homolog 2 (Drosophila) |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SORBS2 | Sorbin and SH3 domain containing 2 |
| SORL1 | Sortilin-related receptor, L(DLR class) A repeats-containing |
| SPAG5 | Sperm associated antigen 5 |
| SPRY2 | Sprouty homolog 2 (Drosophila) |
| SSPN | Sarcospan (Kras oncogene-associated gene) |
| SSRP1 | Structure specific recognition protein 1 |
| STC2 | Stanniocalcin 2 |
| STMN1 | Stathmin 1/oncoprotein 18 |
| SURF2 | Surfeit 2 |
| TACSTD1 | Tumor-associated calcium signal transducer 1 |
| TAT | Tyrosine aminotransferase |
| TBCD | Tubulin-specific chaperone d |
| TGFB3 | Transforming growth factor, beta 3 |
| TIMELESS | Timeless homolog (Drosophila) |
| TIMM17B | Translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| TLR3 | Toll-like receptor 3 |
| TOP2A | Topoisomerase (DNA) II alpha 170 kDa |
| TPX2 | TPX2, microtubule-associated, homolog (Xenopus laevis) |
| TRIP13 | Thyroid hormone receptor interactor 13 |
| TROAP | Trophinin associated protein (tastin) |
| TUBA1 | Tubulin, alpha 1 |
| TXN | Thioredoxin |
| TXNIP | Thioredoxin interacting protein |
| TXNRD1 | Thioredoxin reductase 1 |
| TYRP1 | Tyrosinase-related protein 1 |
| UBE2C | Ubiquitin-conjugating enzyme E2C |
| UBE2V2 | Ubiquitin-conjugating enzyme E2 variant 2 |
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| XPOT | Exportin, tRNA (nuclear export receptor for tRNAs) |
| YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide |
| ZNF238 | Zinc finger protein 238 |
| ZWINT | ZW10 interactor |
| AASS | Aminoadipate-semialdehyde synthase |
Notes: Gene symbol shows the gene symbol of the 283 single genes. Description shows their name.