Figure 1.

A schematic representation of the broad expression of hormone-, peptide-, and energy-related receptors for the major metabolic factors in the olfactory system. The top of the schematic demonstrates cellular and subcellular distribution of factors in the olfactory muscosa; the bottom part demonstrates the same for the olfactory bulb. OSN = olfactory sensory neuron, IR = insulin receptor kinase, Ob-R = leptin receptor, OXR = orexin receptor, GLUT = glucose transporter, CB1 = cannabinoid receptor 1, SUS = sustentacular cells, NPY Y1 = neuropeptide Y receptor Y1, AdipoR = adiponectin receptor, CCK2R = cholecystokinin receptor 2, GHSR = ghrelin receptor, GLP-1R = glucagon-like protein receptor-1, sst-R = somatostatin receptor, MCH-R = melanin-concentrating hormone receptor, NMB-R = neuromedin B receptor, CRFR2 = corticotropin-releasing factor receptor-2.