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. 2012 Dec 17;6:429–464. doi: 10.2147/BTT.S36707

Figure 6.

Figure 6

Network diagram for ACR20/50/70 outcomes for bDMARD monotherapy.

Notes: 1, Combe 2006; 2, Edwards 2004; 3, Johnsen 2006; 4, Kameda 2010 (JESMR); 5, Keystone 2009 (GO-FORWARD); 6, Maini 2006 (CHARISMA); 7, Miyasaka 2008 (Change); 8, Moreland 1997; 9, Moreland 1999; 10, Nishimoto 2004 (STREAM); 11, Nishimoto 2009 (SATORI); 12, van de Putte 2003; 13, van de Putte 2004; 14, van Riel 2006 (ADORE). Placebo 6 arms, 444 patients; MTX 4 arms, 488 patients; etanercept 2 × 25 mg/week, 5 arms, 441 patients; tocilizumab 8 mg/kg/4 weeks, 3 arms, 168 patients; adalimumab 40 mg/2 weeks, 2 arms, 204 patients; sulfasalazine 1 arm, 50 patients.