Table 7.
Comparison of model fit for base case combination therapy network meta-analysis models
| Analysis | DIC | Average residual deviance†† | SD in treatment effects |
|---|---|---|---|
| ACR 20 combination DMARD-experienced (fixed effect) | 615.154 | 1.306 | NA |
| ACR 20 combination DMARD-experienced (random effects) | 607.278 | 1.071 | 0.3151 |
| ACR 50 combination DMARD experienced (fixed effect) | 591.925 | 1.302 | NA |
| ACR 50 combination DMARD-experienced (random effects) | 579.904 | 1.015 | 0.4022 |
| ACR 70 combination DMARD-experienced (fixed effect with cc) | 530.861 | 1.272 | NA |
| ACR 70 combination DMARD-experienced (random effects with cc) | 521.232 | 1.028 | 0.5047 |
| ACR 70 combination DMARD-experienced (fixed effect no cc) | DNC | ||
| ACR 70 combination DMARD-experienced (random effects no cc) | DNC |
Note:
††
Sum of the residual deviance divided by total number of arms.
Abbreviations: NA, not applicable to fixed-effect models; DNC, did not converge; cc, continuity correction; DIC, deviance information criterion; SD, standard deviation.