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. Author manuscript; available in PMC: 2013 Dec 5.
Published in final edited form as: Cell Metab. 2012 Nov 15;16(6):765–776. doi: 10.1016/j.cmet.2012.10.016

Figure 2. Ablation of TFAM protects mice from obesity.

Figure 2

Body weight of male Lox and F-TFKO mice upon chow diet (CD) (A) or high fat diet (HFD) (B) (n=6/genotype/diet). Representative sections of BAT and WAT from 4 month old Lox and F-TFKO mice on CD (C) and HFD (D) (stained with hematoxylin and eosin. Pictures were taken at 20X). 3H] 2-deoxyglucose uptake (E) and glycerol release (F) for isolated white adipocytes from lox and F-TFKO animals at 12 weeks of age (n=6/genotype). (G) 14C-Palmitate oxidation by isolated brown adipocytes (BA) and white adipocytes (WA) of 10-12 weeks old lox and F-TFKO mice (n=6/genotype). Values are given as mean ± SEM, * p<0.05.