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. 2012 Jun 13;129(2):363–371. doi: 10.1093/toxsci/kfs199

Fig. 5.

Fig. 5.

Silencing JNK or Stat3 reduces the migration of neighboring cells induced by cells treated with As3+. (A) siRNA transfection and cell cocultures were performed as described in the Materials and Methods section. Data shown are representative microscopic images of the migrated cells induced by the control cells, cells treated with As3+ for 8 h, and cells transfected with control siRNA (siCon), JNK siRNA (siJNK), or Stat3 siRNA (siStat3) prior to As3+ treatment. (B) Quantification of the migrated neighboring cells. Data are expressed as mean ± SD, n = 5.