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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: J Nutr Biochem. 2012 Sep 17;24(6):1019–1027. doi: 10.1016/j.jnutbio.2012.07.010

Figure 3.

Figure 3

Effect of dietary ABA-supplementation on lung histopathology. Wild-type (WT) or cKO mice were fed either a control or pre-treated with ABA and infected with influenza 104 TCID50 of A/Udorn (H3N2) virus. ABA treatment did not ameliorate epithelial necrosis (A), but it diminished perivascular infiltration (C) as well as the infiltration of the terminal respiratory airways mucosa and submucosa (D) when compared to control-fed mice. The lower number of inflammatory cells in the lungs of ABA-treated WT mice correlated with downregulation of monocyte chemo attractant protein-1 (MCP-1) mRNA following infection when compared to control-fed mice(E). Data points with an asterisk (P<0.05) are significantly different (n=10 mice per treatment and genotype).