Table 2. Intervention scenarios.
Param. | VMB model | PrEP model | ||||
---|---|---|---|---|---|---|
Scenario | Coverage | Resistance1 | Adherence2 | Coverage | Resistance1 | Adherence2 |
Sc1 | 40%-50% | 0.33-0.5 | 50%-60% | 40%-50% | 0.33-0.5 | 70%-80% |
Sc2 | 40%-50% | 0.33-0.5 | 70%-80% | 40%-50% | 0.33-0.5 | 90%-100% |
Sc3 | 40%-50% | 1-2 | 50%-60% | 40%-50% | 1-2 | 70%-80% |
Sc4 | 40%-50% | 1-2 | 70%-80% | 40%-50% | 1-2 | 90%-100% |
Sc5 | 70%-80% | 0.33-0.5 | 50%-60% | 70%-80% | 0.33-0.5 | 70%-80% |
Sc6 | 70%-80% | 0.33-0.5 | 70%-80% | 70%-80% | 0.33-0.5 | 90%-100% |
Sc7 | 70%-80% | 1-2 | 50%-60% | 70%-80% | 1-2 | 70%-80% |
Sc8 | 70%-80% | 1-2 | 70%-80% | 70%-80% | 1-2 | 90%-100% |
Annual rate of resistance development (rmax).
The adherence metric assesses the proportion of sex acts in which each user is protected by VMB or the relative PrEP efficacy due to imperfect adherence compared to perfect adherence.
VMB, vaginal microbicides; PrEP, oral pre-exposure prophylaxis.