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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2013 Jan 1;62(1):95–101. doi: 10.1097/QAI.0b013e3182785638

Table 2. Intervention scenarios.

Param. VMB model PrEP model
Scenario Coverage Resistance1 Adherence2 Coverage Resistance1 Adherence2
Sc1 40%-50% 0.33-0.5 50%-60% 40%-50% 0.33-0.5 70%-80%
Sc2 40%-50% 0.33-0.5 70%-80% 40%-50% 0.33-0.5 90%-100%
Sc3 40%-50% 1-2 50%-60% 40%-50% 1-2 70%-80%
Sc4 40%-50% 1-2 70%-80% 40%-50% 1-2 90%-100%
Sc5 70%-80% 0.33-0.5 50%-60% 70%-80% 0.33-0.5 70%-80%
Sc6 70%-80% 0.33-0.5 70%-80% 70%-80% 0.33-0.5 90%-100%
Sc7 70%-80% 1-2 50%-60% 70%-80% 1-2 70%-80%
Sc8 70%-80% 1-2 70%-80% 70%-80% 1-2 90%-100%
1

Annual rate of resistance development (rmax).

2

The adherence metric assesses the proportion of sex acts in which each user is protected by VMB or the relative PrEP efficacy due to imperfect adherence compared to perfect adherence.

VMB, vaginal microbicides; PrEP, oral pre-exposure prophylaxis.