Table 1.
Risk of subsequent mortality due to ALS after cancer by cancer site and latency in whites in 16 SEER registries
Cancer site | O | 1–4 years
|
5–9 years
|
≥10 years
|
Total
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SMR | 95 % CI | O | SMR | 95 % CI | O | SMR | 95 % CI | O | SMR | 95 % CI | PYR | ||
All cancers (excluding nonmelanoma skin) | 534 | 1.00 | 0.92–1.09 | 356 | 1.01 | 0.91–1.12 | 326 | 1.00 | 0.89–1.11 | 1,216 | 1.00 | 0.95–1.06 | 16,613,508 |
Tongue | 8 | 3.17 | 1.36–6.24 | 3 | 1.94 | 0.39–5.67 | 3 | 2.20 | 0.44–6.42 | 14 | 2.57 | 1.41–4.32 | 80,669 |
Colon | 52 | 1.03 | 0.77–1.34 | 37 | 1.14 | 0.80–1.57 | 32 | 1.02 | 0.70–1.44 | 121 | 1.06 | 0.88–1.26 | 1,312,300 |
Rectum | 13 | 0.95 | 0.50–1.62 | 5 | 0.58 | 0.19–1.34 | 9 | 1.02 | 0.47–1.94 | 27 | 0.87 | 0.57–1.26 | 376,420 |
Bronchus and lung | 25 | 0.95 | 0.62–1.41 | 14 | 1.24 | 0.68–2.09 | 5 | 0.59 | 0.19–1.19 | 44 | 0.96 | 0.70–1.29 | 558,556 |
Female breast | 93 | 1.11 | 0.89–1.36 | 59 | 0.93 | 0.71–1.20 | 77 | 1.08 | 0.85–1.35 | 229 | 1.05 | 0.91–1.19 | 3,757,698 |
Uterine corpus | 22 | 1.14 | 0.72–1.73 | 17 | 0.96 | 0.56–1.53 | 37 | 1.23 | 0.86–1.69 | 76 | 1.13 | 0.89–1.42 | 991,734 |
Prostate | 150 | 0.90 | 0.76–1.06 | 93 | 0.84 | 0.68–1.03 | 46 | 0.77 | 0.57–1.03 | 289 | 0.86 | 0.76–0.96 | 2,864,323 |
Urinary bladder | 36 | 0.95 | 0.66–1.31 | 28 | 1.10 | 0.73–1.59 | 25 | 1.02 | 0.66–1.51 | 89 | 1.01 | 0.81–1.25 | 935,406 |
Kidney parenchyma/renal pelvis | 7 | 0.57 | 0.23–1.18 | 10 | 1.35 | 0.65–2.48 | 8 | 1.16 | 0.50–2.02 | 25 | 0.94 | 0.61–1.39 | 366,216 |
Melanoma of the skin | 27 | 1.34 | 0.88–1.95 | 26 | 1.85 | 1.20–2.70 | 25 | 1.37 | 0.89–2.02 | 78 | 1.49 | 1.17–1.85 | 1,004,503 |
All leukemia | 13 | 1.22 | 0.65–2.09 | 10 | 1.73 | 0.83–3.18 | 1 | 0.24 | 0–1.35 | 24 | 1.17 | 0.75–1.74 | 362,607 |
Non-Hodgkin’s lymphoma | 16 | 0.83 | 0.48–1.35 | 12 | 1.12 | 0.58–1.95 | 11 | 1.28 | 0.64–2.30 | 39 | 1.01 | 0.72–1.38 | 592,704 |
O observations, SMR standardized mortality ratio, PYR person-years