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. Author manuscript; available in PMC: 2013 Dec 21.
Published in final edited form as: Chem Biol. 2012 Nov 8;19(12):1535–1545. doi: 10.1016/j.chembiol.2012.09.019

Figure 2.

Figure 2

Carfilzomib fails to effectively block parasite growth in vivo. Female Balb/c mice infected with 1×106 P. berghei parasites via tail vein injection were dosed intravenously with vehicle (n=4), 0.5 mg/kg carfilzomib (n=3) or 1 mg/kg carfilzomib (n=3) on 3 consecutive days (as indicated by line below the x-axis). Parasitemia was quantified by microscopy counting of Giemsa-stained thin blood smears. The asterisk represents p < 0.05.