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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: J Immunol. 2012 Nov 30;190(1):447–457. doi: 10.4049/jimmunol.1201641

Table III.

Comparison of skewed Vβ13 CDR3-size lengths in the anti-CBA and anti-MMC6 response in the spleen versus the intestines or recipient mice.

160 163 166 169 172 175 178
α-CBA, spleen - - - - - - -
α-MMC6, spleen + + + - - - -
α-CBA, intestine - - - + - - -
α-CBA/MMC6 pre-sensitized, spleena + - + - - - -
α-CBA/MMC6 pre-sensitized, intestinea - - + - - - -
a

Lethally irradiated CBA recipients were injected i.v. with 2 × 107 MMC6 pre-sensitized CD8+ B10.BR T cells. 10 days post-BMT, GVHD-target tissue infiltrating CD8+ T cells were isolated and CDR3-size spectratype analysis was performed as described in Materials and Methods. Skewing of bands was defined as an average peak area greater than the average control area plus 5×SD. —, No skewing; +, skewed CDR3-size length. Results were averaged from 3 separate groups of 3-5 mice/group.