Table 3.
Multivariable odds ratios and 95 % confidence intervals for the associations between smoking and risk of NHL and NHL subtypes in the pooled InterLymph data set
| Non-Hodgkin Lymphoma | Follicular Lymphoma |
DLBCLb | CLL/SLLb | MZLb | MCLb | PTCLb | MF/SSb | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases/controls | ORa (95 % CI) |
Cases | OR | Cases | OR | Cases | OR | Cases | OR | Cases | OR | Cases | OR | Cases | OR | |
| Smoking status | ||||||||||||||||
| Never | 2,278/2,082 | 1.00 | 521 | 1.00 | 705 | 1.00 | 469 | 1.00 | 142 | 1.00 | 75 | 1.00 | 66 | 1.00 | 32 | 1.00 |
| Current | 922/893 | 0.99 (0.89–1.11) |
278 | 1.34 (1.12–1.59) |
248 | 0.86 (0.73–1.02) |
161 | 0.82 (0.67–1.01) |
60 | 1.11 (0.80–1.53) |
40 | 1.18 (0.78–1.77) |
35 | 1.14 (0.74–1.74) |
14 | 0.82 (0.43–1.57) |
| Former | 1,826/1,655 | 1.01 (0.92–1.11) |
377 | 0.94 (0.81–1.09) |
558 | 1.01 (0.89–1.15) |
390 | 0.97 (0.82–1.13) |
110 | 1.07 (0.82–1.39) |
80 | 1.16 (0.83–1.62) |
57 | 1.22 (0.84–1.77) |
34 | 1.39 (0.84–2.30) |
| phomogeneity by study | 0.70 | 0.59 | 0.85 | 0.62 | 0.90 | 0.67 | 0.86 | 0.58 | ||||||||
a
Adjusted for age, sex and study center
b
Subtype abbreviations: DLBCL diffuse large B cell lymphoma, CLL/SLL chronic lymphocytic leukemia/small lymphocytic lymphoma, MZL marginal zone lymphoma, MCL mantle cell lymphoma, PTCL peripheral T cell lymphoma, MF/SS mycosis fungoides/sezary syndrome