TABLE 1.
Clinical and Laboratory Findings in Children With TMP-SMX ADRs at Our Institution
| ED (N = 69) | Hospitalized (N = 40) | P | |
|---|---|---|---|
| Age, y, mean | 8.36 | 9.41 | |
| Boy, n (%) | 21 (30) | 19 (48) | .08 |
| Clinical signs, n (%) | |||
| Rash | 66 (96) | 37 (93) | .49 |
| Mucous membrane involvement | 5 (7) | 19 (48) | <.01 |
| Documented fever | 4 (6) | 23 (58) | <.01 |
| Mental status changes | 0 (0) | 2 (5) | .13 |
| Vomiting | 4 (6) | 12 (30) | <.01 |
| Diarrhea | 0 (0) | 6 (15) | <.01 |
| Laboratory findings, n (%) | |||
| White blood cell count <4.5 | 4/7 (57) | 11/38 (29) | .20 |
| Hemoglobin level <10.5 | 0/7 (0) | 10/38 (26) | .32 |
| Platelet count <150 | 1/7 (14) | 11/38 (29) | .66 |
| Alanine aminotransferase >100 | 0/5 (0) | 9/31 (29) | .30 |