Skip to main content
. Author manuscript; available in PMC: 2014 Jan 25.
Published in final edited form as: Mol Pharm. 2012 Jul 25;9(8):2187–2196. doi: 10.1021/mp300037t

Figure 3. Gene expression enhanced by ultrasound (US) with microbubbles (MBs).

Figure 3

150 µg pGL4 mixed with 10 Vol% or sham Definity® was injected through a portal vein branch into the medial lobe of rat liver for 45 sec, with initially coincident or sham US exposure (1.1 MHz, 2.7 MPa peak negative pressure, 20 cycle pulses, 13.9 Hz PRF), which continued after injection for a total acoustic exposure time of 90 sec. Luciferase expression was measured in extracts from the treated lobe. Error bars indicate SEM (n=6).