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. Author manuscript; available in PMC: 2014 Jan 25.
Published in final edited form as: Mol Pharm. 2012 Jul 25;9(8):2187–2196. doi: 10.1021/mp300037t

Table 2.

Acoustic parameters used (PNP 2.7MPa) in the study of inter-pulse periods (upper panel) and the study of pulse-train US exposure (lower panel).

Pulse Duration (µs) Inter-Pulse Period (ms) PRF While ‘On’ (Hz) Total acoustic Exposure (ms)
18 (20 cycles) 72 13.9 22.5
100 (110 cycles) 400 2.5 22.5
200 (220 cycles) 800 1.25 22.5
500 (550 cycles) 2000 0.5 22.5
1000 (1100 cycles) 4000 0.25 22.5
Gated Pulsing ‘On’
Time (s)
Gated Pulsing
‘Off’ Time (s)
Pulse
Duration(µs)
Inter-Pulse
Period (ms)
PRF While
‘On’ (Hz)
Total acoustic
Exposure (ms)
continuous 0 18 72 13.9 22.5
1 2 18 72 13.9 7.5
2 2 18 72 13.9 11.2
2 3 18 72 13.9 9
3 2 18 72 13.9 13.5

continuous 0 18 18 55.6 90
1 2 18 18 55.6 30
2 2 18 18 55.6 45
2 3 18 18 55.6 36
3 2 18 18 55.6 54