Table 1.

Sample Description: Overall Group

	Mean ± SD or %
Number of patients	80

Age (years)	46.4 ± 14.0^a

Gender (% female)	63.7

Race/ethnicity (%)
Asian	11.3
Black	1.3
Hispanic	5.0
White	80.0
Other/unspecified	2.5

Marital status (%)
Single	28.7
Married	55.0
Divorced/separated	16.3

*Education^ (%)**
High school or less	5.1
Some college	30.8^a, ^b
College degree	32.1^a
Graduate degree	32.1^b

Employment (%)
Full-time	40.0
Part-time	7.5
Unemployed/student/homemaker	35.0
Disabled	12.5
Retired	5.0

Diagnosis (%)
Bipolar I Disorder	53.8
Bipolar II Disorder	41.3
Bipolar Disorder NOS	5.0

*Lifetime Comorbidity^ (%)**
Any psychiatric disorder	65.8
Any anxiety disorder	50.6
Post-traumatic stress disorder ^**	11.7
Alcohol use disorder	19.0
Substance use disorder	20.3
Personality disorder	3.8^a, ^c
Eating disorder	17.7

Clinical Characteristics
Onset age (years) ^*	19.8 ± 9.4^a
Illness duration (years) ^*	26.8 ± 15.0^a, ^b
*Psychosis (lifetime)^ (%)**	46.8
*Psychiatric Hospitalization^ (lifetime) (%)**	59.0
*Rapid cycling (lifetime)^ (%)**	46.8
Rapid cycling (prior year) (%)	2.5
Visit frequency (prior year) (days)	58 ± 38
Number of psychotropic medications (prior year)	3.7 ± 1.9
MPY-CGI-BP-OS score (prior year)	3.1 ± 0.9
Syndromal mood episode (prior year) (%)	51.2
Syndromal/subsyndromal mood symptoms (at enrollment) (%)	25.0

Data missing for one patient.

^**

Data missing for 3 patients.

p < 0.05 CTQ-sexual versus no CTQ-sexual;

p < 0.05 CTQ-physical versus no CTQ-physical;

p < 0.05 BDNF met allele carriers versus non-met allele carriers.