Table 1.
Patient Characteristics
| Factor | Age<13 | Age 13–30 | p-value | |
|---|---|---|---|---|
| N | 127 | 74 | 53 | |
| Age | <.01 | |||
| Median (range) | 9.97 (0.47–29.37) | 5.74 (0.47–12.53) | 17.70 (13.05–29.37) | |
| Gender | 0.82 | |||
| Male | 80 | 46 (62%) | 34 (65%) | |
| Donor source | 0.96 | |||
| Bone Marrow | 55 | 34 (46%) | 21 (40%) | |
| Related Donor | 32 | 17 (50%) | 15 (71%) | 0.08 |
| MURD | 19 | 15 (44%) | 4 (19%) | |
| MMURD | 4 | 2 (6%) | 2 (10%) | |
| Related PBSC | 7 | 2 (3%) | 5 (10%) | |
| Umbilical Cord Blood | 65 | 38 (51%) | 27 (51%) | |
| Single | 42 | 33 (87%) | 9 (33%) | <.01 |
| Double | 23 | 5 (13%) | 18 (67%) | |
| CR Status | 0.22 | |||
| CR1 | 42 | 20 (27%) | 22 (42%) | |
| CR2 | 70 | 45 (60%) | 25 (47%) | |
| CR3 | 15 | 9 (12%) | 6 (11 %) | |
| Recipient CMV | 0.01 | |||
| Negative | 66 | 46 (62%) | 20 (38%) | |
| Positive | 61 | 28 (38%) | 33 (62%) | |
| Ph + | .33 | |||
| Yes | 19 | 13 (18%) | 6 (11 %) | |
| No | 108 | 61 (82%) | 47 (89%) | |
| MLL-R | .79 | |||
| Yes | 11 | 6 (8%) | 5 (9%) | |
| No | 116 | 68 (92%) | 48 (91%) | |
| GVH prophylaxis | .18 | |||
| CSA | 3 | 3 (4%) | 0 | |
| CSA/MMF | 44 | 21 (28%) | 23 (43%) | |
| CSA/MTX | 56 | 32 (43%) | 24 (45%) | |
| CSA/PD/ATG | 19 | 15(20%) | 4 (8%) | |
| ELUTRIATION | 5 | 3 (4%) | 2 (4%) |