FIGURE 5.

Total B cells and CD27⁺ memory B cells correlate with corrected T₁ titers for influenza vaccination in patients but not in healthy controls. A, Scatter plots representing the correlations of number and percentage of total and CD27⁺ memory B cells with mean corrected T₁ titers in all subjects (left panels), controls (center panels), and patients (right panels). Box-and-whisker plots on each axis show median, IQR, and 95% confidence interval for the represented variable. Lines in the plots represent the linear regression for any given pair of variables. Thick continuous lines represent significant correlations. *Number of B cells/μl; ^†percentage of B cells in PBMCs; ^‡number of CD27⁺ memory B cells/μl; ^§percentage of CD27⁺ memory B cells in PBMCs; ^||percentage of CD27⁺ memory B cells in B cells. B, Scatter plots representing the correlations between the number and percentage of total and CD27⁺ B cells with corrected T₁ titers for each influenza strain in patients. Correlations with the H3N2 strain are in the left panels, correlations with H1N1 are in the center panels, and correlations with B are in the right panels. Graph characteristics are the same as in A.