Table II.
Pre- and postvaccination parameters in patients and controls
| Prevaccination Parameters | Patients (n = 31) | Controls (n = 34) | p Value (Patients versus Controls)b |
|---|---|---|---|
| Strain: A/H3N2 | |||
| GMT | 22.4 | 42.5 | 0.001 |
| Seroprotection rate | 39% (12/31) | 74% (25/34) | 0.005 |
| Strain: A/H1N1 | |||
| GMT | 21.9 | 23.1 | 0.72 |
| Seroprotection rate | 39% (12/31) | 47% (16/34) | 0.50 |
| Strain: B | |||
| GMT | 11.6 | 11.5 | 0.93 |
| Seroprotection rate | 10% (3/31) | 12% (4/34) | 1.00 |
| Postvaccination Parameters | |||
| Strain: A/H3N2 | |||
| GMT | 36.6a | 135.9a | <0.00001 |
| Seroconversion rate | 23% (7/31) | 53% (18/34) | 0.012 |
| Seroprotection rate | 65% (20/31) | 94% (32/34) | 0.004 |
| MFI | 1.6 | 3.2 | |
| Strain: A/H1N1 | |||
| GMT | 41.8a | 104.3a | 0.004 |
| Seroconversion rate | 29% (9/31) | 41% (14/34) | 0.31 |
| Seroprotection rate | 74% (23/31) | 94% (32/34) | 0.039 |
| MFI | 1.9 | 4.5 | |
| Strain: B | |||
| GMT | 15.6a | 27.7a | 0.004 |
| Seroconversion rate | 3% (1/31) | 29% (10/34) | 0.005 |
| Seroprotection rate | 23% (7/31) | 44% (15/34) | 0.07 |
| MFI | 1.3 | 2.4 | |
a
p < 0.01 compared with prevaccination GMT.
b
The p values < 0.05 (significant difference) are bold.