Comparison of natural killer (NK) cell subsets in the peripheral blood of human immunodeficiency virus(HIV)-infected patients and healthy controls. (a,b) Gating of NK cells subsets in representative subjects is shown. NK cells from chronic viraemic HIV-1-positive individuals [CD14negCD3neg peripheral blood mononuclear cells (PBMC) gate] were classified into three subsets: CD16posCD56dim, CD56bright and CD16posCD56neg. (c–f) The expression levels of total NK cells and the CD16posCD56dim, CD56bright and CD16posCD56neg subsets, respectively, in former plasma donors (FPDs) with different groups and in healthy controls.