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. 2012 Sep 17;590(Pt 23):6213–6226. doi: 10.1113/jphysiol.2012.233676

Figure 2. Wheel access altered daily rhythms of heart rate (HR) in WT mice.

Figure 2

A, double-plotted raster plot of HR using 10 consecutive days of HR recording from the same WT mouse subjected to the four wheel-access conditions in the presence of a 12 h–12 h light–dark cycle. B, group mean waveforms using 10 days of HR recordings from WT mice (n= 7) subjected to the various wheel-access conditions. The HR data were grouped into 3 h bins. Heart rates were increased at most time points of the light–dark cycle, including periods when the wheel was available. For statistical results, see Supplemental Table 2. C, increased power of HR rhythms in WT mice subjected to early night wheel access. Power measurement was produced by periodogram analysis using 10 days of HR data. D, late night access delayed the acrophase of HR rhythms of WT mice. Error bars are SEM (*P < 0.05).