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. 2012 Sep 17;590(Pt 23):6213–6226. doi: 10.1113/jphysiol.2012.233676

Figure 6. Effects of wheel access on amplitude of PER2::LUC rhythms in the SCN of VIP-deficient mice.

Figure 6

A, example bioluminescence waveforms from VIP-deficient mice subjected to the wheel-access conditions. B, effects of wheel access on the amplitude of PER2::LUCIFERASE (PER2::LUC) rhythms in the SCN of VIP-deficient mice, where late night wheel access significantly improved the amplitude of PER2::LUC rhythms such that the amplitude was no longer significantly different when compared with WT mice (see main text and Supplemental Table 7). Dotted lines represent WT levels. The average PER2::LUC amplitude was analysed using a one-way ANOVA. Genotypic comparisons were analysed using a two-way ANOVA. Error bars are SEM (*P < 0.05).