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Immunostaining for hyperphosphorylated tau (AT8) in case 5. (A) There is a neurofibrillary tangle ([NFT], arrow) in the pontine nuclei. (B) There is a tufted astrocyte (arrowhead) in the motor cortex. (C) There is a glial cytoplasmic inclusion (open arrow) in the subthalamic nucleus. (D) There is an NFT with labeled processes (arrow) in the internal segment of the globus pallidus. Magnifications: A, C, D, 400x; B, 630x.
