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. Author manuscript; available in PMC: 2013 Dec 21.
Published in final edited form as: Cell. 2012 Dec 21;151(7):1581–1594. doi: 10.1016/j.cell.2012.11.040

Figure 2. Pcdh10 is required for MEF2-induced functional synapse elimination in WT neurons.

Figure 2

(A) Average evoked EPSC amplitude (A1) and mEPSC frequency (A2) from untransfected and control shRNA with MEF2-VP16ERtm transfected CA1 neurons in slice culture (n = 13 for both E1 and E2). (B) Average evoked EPSC amplitude (B1) and mEPSC frequency (B2) from untransfected and Pcdh10 shRNA with MEF2-VP16ERtm transfected cells (n = 16 for both F1 and F2). (C) Average evoked EPSC amplitude (C1) and mEPSC frequency (C2) from untransfected and Pcdh10 shRNA with MEF2-VP16ERtm and shRNA-insensitive Pcdh10 construct transfected cells (n = 24 for both C1 and C2). In all figures, error bars represent SEM. *p < 0.05. Representative evoked EPSC and mEPSC traces are shown with the dot plots of individual cell pairs and on the right of each figure, respectively. See also Figure S2 and Table S1.