Figure 3.

A Kaplan-Meier plot of disease-free status of all 355 patients in the 53-family cohort, including known mutation carriers who are disease free and therefore censored (open circles) at the most recent age of query. Adding the censored members reverses the statistically significant differences by generation noted in the time biased analysis in Figure 2. FPAH = familial pulmonary arterial hypertension.