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CHARACTERISTICS OF FAMILY PEDIGREES WITH BMPR2 MUTATIONS
| Characteristic | Value (N = 355) |
| Median pedigree size in BMPR2 (interquartile range) | 4 (3–8) |
| n (%) in each generation | |
| First | 93 (26) |
| Second | 138 (39) |
| Third | 81 (23) |
| Fourth | 43 (12) |
| Female, n (%) | 226 (64) |
| Affected, n (%) | 249 (70) |
| Age at diagnosis of affecteds, yr (N = 249) | |
| Mean ± SD | 34.9 ± 14.9 |
| Range | 0–74 |
| Age at death or age of last contact in unaffecteds, yr (N = 106) | |
| Mean ± SD | 66.7 ± 15.3 |
| Range | 20–98 |
