Table 3.
Soluble heat shock protein subtype | Number of patients | Cardiovascular disease | Study finding | Reference |
---|---|---|---|---|
HSP70 | 24 | Acute myocardial infarction | Soluble HSP70 is released into the circulation after an acute myocardial infarction | [28] |
HSP60 | 684 | Carotid atherosclerosis | Levels of soluble HSP60 are associated with early carotid atherosclerosis | [29] |
HSP70 | 52 cases 20 controls |
Acute myocardial infarction | Levels of soluble HSP70 are associated with progression of heart failure after acute myocardial infarction | [30] |
HSP60, HSP72 | 88 cases 44 controls |
Idiopathic left ventricular dysfunction | Levels of soluble HSP60 and HSP72 correlate with severity of cardiac and microvascular dysfunction in patients with idiopathic left ventricular dysfunction | [15] |
HSP70 | 167 | Congestive heart failure | Levels of soluble HSP70 are associated with severity of heart failure in patients with congestive heart failure | [31] |
HSP60 | 1003 cases 1003 controls |
Coronary artery disease | Levels of soluble HSP60 correlate with the presence of coronary artery disease | [32] |