Table 5.
Analgesic and Frequency of Use | Age Group, years |
P for Interaction | |||||
---|---|---|---|---|---|---|---|
<50 |
≥50 |
||||||
No. of Cases | RR | 95% CI | No. of Cases | RR | 95% CI | ||
Aspirin, days/week | |||||||
<1 | 3,582 | 1.00 | 3,789 | 1.00 | |||
1 | 209 | 0.97 | 0.84, 1.13 | 161 | 0.97 | 0.83, 1.14 | 0.98 |
2–3 | 161 | 1.06 | 0.90, 1.24 | 258 | 1.08 | 0.95, 1.23 | 0.83 |
4–5 | 81 | 0.90 | 0.72, 1.12 | 194 | 1.03 | 0.89, 1.18 | 0.34 |
≥6 | 279 | 0.95 | 0.84, 1.08 | 1,070 | 1.02 | 0.95, 1.09 | 0.48 |
Ibuprofen, days/week | |||||||
<1 | 2,302 | 1.00 | 3,293 | 1.00 | |||
1 | 824 | 1.02 | 0.94, 1.11 | 659 | 1.01 | 0.92, 1.10 | 0.87 |
2–3 | 752 | 1.11 | 1.01, 1.20 | 808 | 1.15 | 1.06, 1.24 | 0.50 |
4–5 | 252 | 1.25 | 1.10, 1.43 | 298 | 1.18 | 1.05, 1.33 | 0.51 |
≥6 | 259 | 1.48 | 1.29, 1.68 | 346 | 1.10 | 0.99, 1.23 | 0.0007 |
Acetaminophen, days/week | |||||||
<1 | 3,145 | 1.00 | 4,199 | 1.00 | |||
1 | 648 | 1.00 | 0.91, 1.09 | 477 | 1.02 | 0.92, 1.12 | 0.76 |
2–3 | 380 | 1.13 | 1.01, 1.26 | 397 | 1.08 | 0.97, 1.19 | 0.48 |
4–5 | 115 | 1.35 | 1.12, 1.63 | 150 | 1.12 | 0.95, 1.32 | 0.13 |
≥6 | 76 | 1.03 | 0.82, 1.30 | 193 | 1.09 | 0.94, 1.26 | 0.74 |
Abbreviations: CI, confidence interval; RR, relative risk.
a Adjusted for age; race; body mass index; alcohol consumption; physical activity; intakes of alcohol, folate, vitamin B12, magnesium, potassium, and vitamin A; smoking status; hypertension; diabetes; and use of the other analgesics.