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. 2012 Oct 1;176(Suppl 7):S64–S71. doi: 10.1093/aje/kws233

Table 2.

Prevalence of Low Antihypertensive Medication Adherencea Associated With Life Events,b Stratified by Coping Level,c Among CoSMO Participants, 2007–2008

Total Sample No. With Life Event (n = 1,817) Low Medication Adherence, %
High Coping (n = 947; 13.4%) Low Coping (n = 869; 13.6%)
Vacation 748 10.2* 10.5
Death of a close friend 567 16.5* 16.3
Death in the family 467 12.8 15.9
Change in health/behavior of family member 413 18.1 20.3***
Gained a new family member 362 12.4 17.3
Change in amount/type of recreation 320 17.2 19.9**
Change in the number of get-togethers 315 16.3 15.5
Change in financial state 298 20.1* 20.1***
Large purchase 291 12.4 14.9
Change in eating habits 280 13.4 26.7***
Sexual difficulties 266 15.8 17.5
Change in sleeping habits 252 13.1 20.0*
Change in living conditions 226 17.2 15.5
Outstanding personal achievement 214 13.2 14.1
Personal injury or illness 214 15.0 15.0
Change in church activities 213 17.5 19.8*
Change in social activities 195 14.7 22.6*
Change in residence 132 15.5 11.5
Retirement 112 19.7 22.2
Change in number of arguments with spouse 105 12.5 14.3

Abbreviation: CoSMO, Cohort Study of Medication Adherence among Older Adults.

* P < 0.05, **P < 0.01, ***P < 0.001 for comparison of low adherence in those participants experiencing each life event versus those who did not.

a Antihypertensive medication adherence was measured at the 1-year CoSMO follow-up survey by using the Morisky Medication Adherence Scale (MMAS-8): Low medication adherence was defined as an MMAS-8 score of <8.

b Life events reported by <5% of the sample are not listed. Life events over the last year were measured at the 1-year CoSMO follow-up survey by using the Holmes Rahe Social Readjustment Rating Scale (SRRS).

c Coping was measured at the baseline CoSMO survey by using a 7-item coping scale: Low and high coping are defined as scores above and below the median for the sample, respectively. Coping data were not available for 1 participant in the sample.