Table 1.
Characteristics and BP Responses to Sodium Intervention Among 3,142 Participants From 633 Families, GenSalt Study, China, 2003–2005
| Probands (n = 676) |
Spouses (n = 69) |
Parents (n = 1,236)a |
Siblings (n = 956) |
Offspring (n = 205) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| % | Mean (SD) | % | Mean (SD) | % | Mean (SD) | % | Mean (SD) | % | Mean (SD) | |
| Men | 60.4 | 33.3 | 48.6 | 51.1 | 55.6 | |||||
| Age, years | 41.0 (8.3) | 49.1 (6.7) | 67.6 (8.4) | 39.6 (7.7) | 23.5 (6.5) | |||||
| Body mass indexb | 24.2 (3.3) | 23.4 (3.7) | 22.8 (3.4) | 23.1 (2.8) | 21.5 (3.3) | |||||
| Baseline BP, mm Hg | ||||||||||
| SBP | 128.0 (11.4) | 112.6 (14.9) | 136.6 (23.9) | 111.6 (11.5) | 106.6 (10.3) | |||||
| DBP | 80.3 (9.0) | 72.6 (10.0) | 75.0 (11.7) | 71.0 (8.9) | 65.3 (9.0) | |||||
| MAP | 96.2 (8.5) | 85.9 (11.2) | 95.6 (14.3) | 84.5 (9.2) | 79.1 (8.7) | |||||
| BP during low-sodium intervention, mm Hg | ||||||||||
| SBP | 119.9 (11.3) | 106.2 (11.7) | NA | 107.2 (9.8) | 104.5 (9.7) | |||||
| DBP | 76.0 (9.1) | 69.5 (8.7) | NA | 69.1 (8.6) | 63.7 (8.7) | |||||
| MAP | 94.2 (9.3) | 81.7 (9.1) | NA | 81.8 (8.3) | 77.3 (8.2) | |||||
| BP response to low-sodium intervention, mm Hg | ||||||||||
| SBP | −8.0 (7.9) | −5.59 (7.7) | NA | −4.3 (6.0) | −2.3 (4.9) | |||||
| DBP | −4.2 (5.9) | −2.7 (5.0) | NA | −2.0 (5.1) | −1.7 (5.3) | |||||
| MAP | −5.5 (5.8) | −3.7 (5.4) | NA | −2.7 (4.8) | −1.9 (4.5) | |||||
| BP during high-sodium intervention, mm Hg | ||||||||||
| SBP | 125.6 (12.4) | 111.9 (13.4) | NA | 111.8 (11.1) | 106.9 (10.1) | |||||
| DBP | 78.5 (9.4) | 71.3 (9.5) | NA | 70.8 (9.1) | 64.5 (8.7) | |||||
| MAP | 94.2 (9.3) | 84.9 (10.4) | NA | 84.5 (9.2) | 78.7 (8.3) | |||||
| BP response to high-sodium intervention, mm Hg | ||||||||||
| SBP | 5.7 (6.4) | 5.8 (5.9) | NA | 4.7 (5.8) | 2.6 (4.3) | |||||
| DBP | 2.5 (5.8) | 2.0 (4.3) | NA | 1.7 (5.2) | 0.9 (5.0) | |||||
| MAP | 3.3 (4.4) | −2.9 (4.7) | NA | 2.7 (4.8) | 1.4 (4.0) | |||||
Abbreviations: BP, blood pressure; DBP, diastolic blood pressure; GenSalt, Genetic Epidemiology Network of Salt Sensitivity; MAP, mean arterial pressure; NA, not available; SBP, systolic blood pressure; SD, standard deviation.
a Characteristics for parents in the sample. Parents did not take part in the dietary intervention, and their BP responses to sodium intervention are not available.
b Body mass index: weight (kg)/height (m)2.