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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Lancet Infect Dis. 2012 May 30;12(7):531–537. doi: 10.1016/S1473-3099(12)70088-9

Figure 4.

Figure 4

Schematic representation of the interaction of challenge intensity and VE. The black line represents magnitude of protective vaccine induced immunity as it rises after each immunization and wanes subsequently over time.