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. 2012 Dec 26;7(12):e52672. doi: 10.1371/journal.pone.0052672

Figure 2. Global 5mC is increased in spinal cord of sALS.

Figure 2

Genomic DNA extracted from control (open bar) or sALS (filled bar) postmortem human spinal cord was analyzed with an ELISA colorimetric assay for methylation, (5mC; Ctrl = 11, sALS = 11). Outliers, outside of median ±1.5 x Inter-Quartile-Range, were excluded. The data is presented as mean ± SEM of percent (%) 5mC using box and whiskers vertical bars plotting minimum to maximum values. A two-sample equal variance t-test used; ***p<0.001 compared to control group (Ctrl) with an achieved power of 99%.