Table 5. Characteristics of sALS and control subjects used for global 5mC and 5 HmC in whole blood.
Characteristics | sALS group | Control group | p-value | |
Number of subjects | 11 | 12 | – | |
Age (years)(a) | 60 (48–68) | 59 (48–70) | NS | |
Gender | Male | 7 | 7 | NS |
Female | 4 | 5 | NS | |
Onset | Bulbar | 3 | 0 | – |
Limb | 8 | 0 | – | |
Disease duration (months)(a)(b) | 45 (16–64) | – | – | |
Health condition of controls(c) | Anxiety | 0 | 1 | – |
Asthma | 0 | 2 | – | |
Cancer | 0 | 3 | – | |
Healthy | 0 | 5 | – | |
Hearing loss | 0 | 1 | – | |
Hypercholesterolemia | 0 | 1 | – | |
Hypothyroidism | 0 | 2 | – | |
Hypertension | 0 | 1 | – |
median (range);
mean ± standard deviation;
some patients presented more than one condition; NS, not significant; ‘–‘, value not available.