Figure 6. Anion relative permeability and relative slope conductance of the SlitBest1b current.

Whole-cell currents were activated by dialysis with 10 µM free Ca²⁺ and recorded in bath solutions containing either 125 mM NaCl or 125 mM of the substituting NaX. A) Anion relative permeabilities P _X/P _Cl were calculated using the Goldman–Hodgkin–Katz equation from measured differences in E _rev between symmetrical Cl⁻ and bianionic conditions. B) Relative slope conductances G _X/G _Cl were obtained from the measurement of the slope of the I-V relationships between −80 and +80 mV. Four replicates for each condition were obtained. Means ± SEM. *p<0.05; **p<0.01; ***p<0.001.