Skip to main content
. 2012 Dec 26;7(12):e52833. doi: 10.1371/journal.pone.0052833

Figure 1. Overall activation of Notch signaling is increased in the aortic wall of DTAAD patients.

Figure 1

A) Western blot studies showed that the expression of Notch1 (transmembrane/intracellular region NTM, ∼120 kDa) in human aortic tissue was significantly increased in TAA tissue compared with control tissue, and NICD was significantly increased in TAA and TAD samples compared with control. B) Quantitative real-time RT-PCR showed increased expression levels of Notch1 in TAA and TAD samples compared with control. C) Western blot studies showed that the expression of Hes1 in human aortic tissue was significantly increased in TAA and TAD samples compared with control.