Table 1. Significant associations between patient- and caregiver related factors and driving status: Results of univariate statistical analysis.
| Variable | Driving cessation | No driving cessation | p-value |
| N = 145 | N = 95 | ||
| Age, yrs (median, IQR) | 77(71.00–81.00) | 74(67.00–79.00) | 0.037† |
| Female gender (N, %) | 65(44.80) | 30(31.60) | 0.040‡ |
| Retired (N, %) | 132(97.10) | 80(90.90) | 0.046‡ |
| Assistance at home (N, %) | 126(87.50) | 73(76.80) | 0.031‡ |
| MMSE (median, IQR) | 22.00(18.50–25.00) | 24.00(21.00–26.00) | <0.001† |
| CDR (median, IQR) | 1.00(0.50–1.00) | 0.50(0.50–1.00) | <0.001† |
| CERAD Constructional practice (mean, SD) | −0.98 (1.79) | −0.13(1.51) | 0.001# |
| NPI – Aberrant motor behavior (N, %) | 34(23.40) | 12(12.80) | 0.041‡ |
| NPI – Apathy (N, %) | 66(45.80) | 28(29.80) | 0.013‡ |
| DAD (median, IQR) | 67.50(42,50–87.50) | 87.00(72.50–97.50) | <0.001† |
| ZBI (median, IQR) | 22(11.00–32.00) | 13(4.00–24.00) | <0.001† |
SD = Standard Deviation, IQR = interquartile range.
†
Mann-Whitney-U-Test.
‡
χ2 Test. #Student’s t-test. Abbreviations: MMSE = Mini Mental State Examination, CDR = Clinical dementia rating, CERAD = Consortium to establish a registry for Alzheimer’s disease, NPI = Neuropsychiatric Inventory, DAD = Disability Assessment for Dementia, ZBI = Zarit Burden Interview.