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. 2012 Dec 26;7(12):e51967. doi: 10.1371/journal.pone.0051967

Figure 2. Long term treatment of nicotine increases mRNA expression of stem cell genes in head and neck squamous cell carcinoma cell lines UMSCC10B and HN-1.

Figure 2

A) CD44, B) Bmi1, C) Oct4, D) Nanog. E) Effect of nicotine on expression of stem cell markers in normal oral keratinocytes. *p<0.05, **p<0.01.