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. 2012 Dec 26;7(12):e52759. doi: 10.1371/journal.pone.0052759

Figure 7. Thermal denaturation monitored by CD spectroscopy.

Figure 7

Measurement at a single wavelength while increasing temperature reveals the high thermal stability of cleaved human CBG. (A) Rat CBG shows no difference in thermal stability upon cleavage of the RCL. Native rat CBG-WT is shown in green, cleaved rat CBG-RCL1 in blue. The shape of the curves is largely similar. (B) Human CBG shows great differences in thermal stability between cleaved and native protein. The cleaved state of human CBG is highly thermostable (red), while the native state (yellow) shows a curve similar to rat CBG.