Table 4. Abundance and differential expression of the highly abundant caprine miRNAs in the mammary gland.
miRNA name | D | P | D-NE | P-NE | Fold-change log2 P-NE/D-NE | P-value | Sig-label |
miR-2887 | 385 | 1671 | 25.9235 | 106.3458 | 2.0364 | 4.3E−175 | ** |
miR-451 | 749 | 1665 | 50.433 | 105.964 | 1.0711 | 1.25E−68 | ** |
miR-2478 | 869 | 1888 | 58.5131 | 120.1561 | 1.0381 | 8.41E−74 | ** |
miR-199b | 1565 | 290 | 105.3774 | 18.4562 | −2.5134 | 3E−227 | ** |
miR-128 | 8512 | 1408 | 573.1456 | 89.608 | −2.6772 | 0 | ** |
miR-25 | 36578 | 5728 | 2462.937 | 364.5414 | −2.7563 | 0 | ** |
miR-145 | 41213 | 6254 | 2775.029 | 398.0171 | −2.8016 | 0 | ** |
miR-98 | 2531 | 370 | 170.4219 | 23.5475 | −2.8555 | 0 | ** |
miR-222 | 5223 | 734 | 351.6846 | 46.7132 | −2.9124 | 0 | ** |
miR-181b | 5330 | 734 | 358.8893 | 46.7132 | −2.9416 | 0 | ** |
miR-199a-3p | 152691 | 20829 | 10281.27 | 1325.6 | −2.9553 | 0 | ** |
miR-93 | 3593 | 460 | 241.9305 | 29.2753 | −3.0468 | 0 | ** |
miR-221 | 7848 | 790 | 528.4359 | 50.2772 | −3.3938 | 0 | ** |
let-7b | 443620 | 32993 | 29870.63 | 2099.741 | −3.8304 | 0 | ** |
let-7c | 341112 | 27377 | 22968.38 | 1742.327 | −3.7206 | 0 | ** |
P and P-NE represent the actual sequencing count and normalized expression level of miRNAs in the small RNA library generated from the mammary gland during peak lactation, respectively.
D and D-NE represent the actual sequencing count and normalized expression level of miRNAs in the small RNA library generated from the mammary gland during the dry period, respectively.
Fold-change [log2 (P-NE/D-NE)] indicates the fold change of the miRNAs in a pair of samples.
The P-value reflects the significance of the miRNA differential between the samples. A smaller P-value indicates a more significant difference in the miRNA level between samples.
A sig-label of ** indicates a fold-change (log2)>1 or (log2)<-1 and a P-value<0.01.