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. 2012 Dec 26;7(12):e37385. doi: 10.1371/journal.pone.0037385

Table 5. Total genes disrupted by CNVs in each cohort for fluid-type intelligence (gf).

All CNVs Deletions Duplications
Cohort Sample Size Gene Load Rate Gene Load Rate Gene Load Rate
ABC1936 346 37 0.107 8 0.023 29 0.084
LBC1921 482 60 0.125 10 0.021 50 0.104
LBC1936 877 144 0.164 56 0.064 88 0.100
Manchester 730 81 0.111 19 0.026 62 0.085
Newcastle 698 120 0.172 4 0.006 116 0.166
Total 3133 442 0.141 97 0.031 345 0.110

Gene load is calculated as the number of genes whose co-ordinates +/−20 kb intersect with a CNV that passes QC checks (length ≥500 kb, and frequency ≤1%). Rate is the average number of such CNVs per individual.